Multimodality Molecular Imaging of Tumor Angiogenesis
نویسندگان
چکیده
منابع مشابه
Multimodality molecular imaging of tumor angiogenesis.
Molecular imaging is a key component of 21st-century cancer management. The vascular endothelial growth factor (VEGF)/VEGF receptor signaling pathway and integrin alpha v beta 3, a cell adhesion molecule, play pivotal roles in regulating tumor angiogenesis, the growth of new blood vessels. This review summarizes the current status of tumor angiogenesis imaging with SPECT, PET, molecular MRI, ta...
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W. J. Mulder, G. J. Strijkers, C. de Mello Donegá, R. J. Brandwijk, P. T. Chin, R. Koole, K. Castermans, G. Storm, A. W. Griffioen, K. Nicolay Biomedical NMR, Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, Condensed Matter and Interfaces, Utrecht University, Utrecht, Netherlands, Department of Pathology, Maastricht University, Maastricht, Netherlands, Molecu...
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When a tracer, such as Gd-doped or iodinated extracellular contrast, is introduced into the blood stream of a patient its transport through the vascular system, heart and lungs and eventual excretion via the kidneys is a well-established process [1,2]. At the level of the imaging voxel (for example, in the centre of a breast tumor) we can only speculate as to the precise nature of the tracer ki...
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Angiogenesis is an important biological process that is also related to various diseases, such as cancer, cardiovascular and cerebrovascular disease. Currently, the need for angiogenesis imaging is increasing due to the use of anti-angiogenic therapy to treat tumors, and of angiogenesis-inducing therapy to treat vascular diseases. Several techniques can be used to visualize angiogenesis related...
متن کاملMolecular Imaging of Tumor Angiogenesis
Molecular imaging has recently been defined by the Society of Nuclear Medicine as ‘the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems’ (Mankoff 2007). It usually exploits specific labeled molecular probes, as well as intrinsic tissue characteristics as the source of image contrast, and uses a numbe...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2008
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.107.045922